Valency-Based Indices for Some Succinct Drugs by Using M-Polynomial

A topological index, which is a number, connected to graph. It often used in chemometrics, biomedicine, and bioinformatics anticipate various physicochemical properties biological activities of compounds. The purpose this article encourage original research focused on graph indices for the drugs azacitidine, decitabine, guadecitabine as well an investigation genesis symmetry actual networks. Symmetry universal phenomenon that applies nature’s conservation rules complicated systems. Although ubiquitous structural characteristic complex networks, it has only been seldom examined real-world M¯-polynomial, one these polynomials, create number degree-based coindices. Patients with higher-risk myelodysplastic syndromes, chronic myelomonocytic leukemia, acute myeloid leukemia who are not candidates intense regimens, such induction chemotherapy, treated hypomethylating drugs. Examples decitabine (5-aza-20-deoxycytidine), guadecitabine, azacitidine. M¯-polynomial study construct variety coindices three brief medicines suggested. New cancer therapies could be developed using indice knowledge, specifically first Zagreb second F-index, reformulated modified Zagreb, symmetric division inverse sum harmonic augmented index guadecitabine.